專家簡介: 陳建鋒

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我是陽明大學榮陽基因體研究中心的助理研究員 陳建鋒，參事基因體研究多年，特別是在 Cancer Genomic 與 GWAS 的方面，歡迎您來跟我討論。

研究領域：

Genomics, Oncology

學歷：
博士        國防醫學院          生命科學所
碩士        國立清華大學       輻射生物研究所
學士        大同工學院          生物工程系


經歷：
助理研究員          國立陽明大學    榮陽基因體研究中心
博士後研究員        中央研究院      生物醫學研究所


專長：
Chromosome aberration analysis, Gene expression analysis, Genotyping analysis, Public domai

研究成果：

  1. Yang, C.Y., Tseng, J.Y., Chen, C.F. *, Chou, T.Y., Gao, H.W., Hua, C.L., Lin, C.H., Lin, J.K., and Jiang, J.K., Genome-wide copy number changes and CD133 expression characterized distinct subset of colon polyps: differentiation between incidental polyps and cancer-associated polyps. Int J Colorectal Dis, 2015. (* Equal first author)
  2. Sudhir, P.R., Lin, S.T., Chia-Wen, C., Yang, S.H., Li, A.F., Lai, R.H., Wang, M.J., Chen, Y.T., Chen, C.F., Jou, Y.S., and Chen, J.Y., Loss of PTPRM associates with the pathogenic development of colorectal adenoma-carcinoma sequence. Sci Rep, 2015. 5: p. 9633.
  3. Chou, C.P., Huang, N.C., Jhuang, S.J., Pan, H.B., Peng, N.J., Cheng, J.T., Chen, C.F., Chen, J.J., and Chang, T.H., Ubiquitin-Conjugating Enzyme UBE2C Is Highly Expressed in Breast Microcalcification Lesions. Plos One 2014. 9(4): p. e93934.
  4. Wang, Y.W., Lin, K.T., Chen, S.C., Gu, D.L., Chen, C.F., Tu, P.H., and Jou, Y.S., Overexpressed-eIF3I interacted and activated oncogenic Akt1 is a theranostic target in human hepatocellular carcinoma. Hepatology, 2013. 58(1): p. 239-50.
  5. Gu, D.L., Chen, Y.H., Shih, J.H., Lin, C.H., Jou, Y.S., and Chen, C.F., Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma. World J Gastroenterol, 2013. 19(47): p. 8873-8879.
  6. Kao, S., Shiau, C.K., Gu, D.L., Ho, C.M., Su, W.H., Chen, C.F., Lin, C.H., and Jou, Y.S., IGDB.NSCLC: integrated genomic database of non-small cell lung cancer. Nucleic Acids Res, 2012. 40(Database issue): p. D972-7.
  7. Shiau, C.K., Gu, D.L., Chen, C.F., Lin, C.H., and Jou, Y.S., IGRhCellID: integrated genomic resources of human cell lines for identification. Nucleic Acids Res, 2011. 39(Database issue): p. D520-4.
  8. Chen, C.F., Hsu, E.C., Lin, K.T., Tu, P.H., Chang, H.W., Lin, C.H., Chen, Y.J., Gu, D.L., Wu, J.Y., Chen, Y.T., Hsu, M.T., and Jou, Y.S., Overlapping high-resolution copy number alterations in cancer genomes identified putative cancer genes in hepatocellular carcinoma. Hepatology, 2010. 52(5): p. 1690-701.
  9. Chen, C.F., Yeh, S.H., Chen, D.S., Chen, P.J., and Jou, Y.S., Molecular genetic evidence supporting a novel human hepatocellular carcinoma tumor suppressor locus at 13q12.11. Genes Chromosomes Cancer, 2005. 44(3): p. 320-8.
  10. Lee, J.M., Chung, C.Y., Chiang, W.W., Liou, Y.H., Chen, C.F., and Liao, N.S., IL-15Ralpha is a negative regulator of TCR-activated proliferation in CD4+ T cells. J Immunol, 2004. 173(5): p. 3155-64.
  11. Jou, Y.S., Lee, C.S., Chang, Y.H., Hsiao, C.F., Chen, C.F., Chao, C.C., Wu, L.S., Yeh, S.H., Chen, D.S., and Chen, P.J., Clustering of minimal deleted regions reveals distinct genetic pathways of human hepatocellular carcinoma. Cancer Res, 2004. 64(9): p. 3030-6.

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