我是陽明大學榮陽基因體研究中心的助理研究員 陳建鋒,參與基因體研究多年,特別是在Cancer Genomic與GWAS的方面,歡迎您來跟我討論。
研究領域:
Genomics, Oncology
學歷:
國防醫學院生命科學所博士
國立清華大學輻射生物研究所碩士
大同工學院生物工程系學士
經歷:
國立陽明大學榮陽基因體研究中心助理研究員
中央研究院生物醫學研究所博士後研究員
專長:
Chromosome aberration analysis
Gene expression analysis
Genotyping analysis, Public domai
研究成果:
1. Yang, C.Y., Tseng, J.Y., Chen, C.F. , Chou, T.Y., Gao, H.W., Hua, C.L., Lin, C.H., Lin, J.K., and Jiang, J.K., Genome-wide copy number changes and CD133 expression characterized distinct subset of colon polyps: differentiation between incidental polyps and cancer-associated polyps. Int J Colorectal Dis, 2015. ( Equal first author)
2. Sudhir, P.R., Lin, S.T., Chia-Wen, C., Yang, S.H., Li, A.F., Lai, R.H., Wang, M.J., Chen, Y.T., Chen, C.F., Jou, Y.S., and Chen, J.Y., Loss of PTPRM associates with the pathogenic development of colorectal adenoma-carcinoma sequence. Sci Rep, 2015. 5: p. 9633.
3. Chou, C.P., Huang, N.C., Jhuang, S.J., Pan, H.B., Peng, N.J., Cheng, J.T., Chen, C.F., Chen, J.J., and Chang, T.H., Ubiquitin-Conjugating Enzyme UBE2C Is Highly Expressed in Breast Microcalcification Lesions. Plos One 2014. 9(4): p. e93934.
4. Wang, Y.W., Lin, K.T., Chen, S.C., Gu, D.L., Chen, C.F., Tu, P.H., and Jou, Y.S., Overexpressed-eIF3I interacted and activated oncogenic Akt1 is a theranostic target in human hepatocellular carcinoma. Hepatology, 2013. 58(1): p. 239-50.
5. Gu, D.L., Chen, Y.H., Shih, J.H., Lin, C.H., Jou, Y.S., and Chen, C.F., Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma. World J Gastroenterol, 2013. 19(47): p. 8873-8879.
6. Kao, S., Shiau, C.K., Gu, D.L., Ho, C.M., Su, W.H., Chen, C.F., Lin, C.H., and Jou, Y.S., IGDB.NSCLC: integrated genomic database of non-small cell lung cancer. Nucleic Acids Res, 2012. 40(Database issue): p. D972-7.
7. Shiau, C.K., Gu, D.L., Chen, C.F., Lin, C.H., and Jou, Y.S., IGRhCellID: integrated genomic resources of human cell lines for identification. Nucleic Acids Res, 2011. 39(Database issue): p. D520-4.
8. Chen, C.F., Hsu, E.C., Lin, K.T., Tu, P.H., Chang, H.W., Lin, C.H., Chen, Y.J., Gu, D.L., Wu, J.Y., Chen, Y.T., Hsu, M.T., and Jou, Y.S., Overlapping high-resolution copy number alterations in cancer genomes identified putative cancer genes in hepatocellular carcinoma. Hepatology, 2010. 52(5): p. 1690-701.
9. Chen, C.F., Yeh, S.H., Chen, D.S., Chen, P.J., and Jou, Y.S., Molecular genetic evidence supporting a novel human hepatocellular carcinoma tumor suppressor locus at 13q12.11. Genes Chromosomes Cancer, 2005. 44(3): p. 320-8.
10. Lee, J.M., Chung, C.Y., Chiang, W.W., Liou, Y.H., Chen, C.F., and Liao, N.S., IL-15Ralpha is a negative regulator of TCR-activated proliferation in CD4+ T cells. J Immunol, 2004. 173(5): p. 3155-64.
11. Jou, Y.S., Lee, C.S., Chang, Y.H., Hsiao, C.F., Chen, C.F., Chao, C.C., Wu, L.S., Yeh, S.H., Chen, D.S., and Chen, P.J., Clustering of minimal deleted regions reveals distinct genetic pathways of human hepatocellular carcinoma. Cancer Res, 2004. 64(9): p. 3030-6.