{"id":148,"date":"2025-06-24T06:44:13","date_gmt":"2025-06-24T06:44:13","guid":{"rendered":"https:\/\/genoinfocore.crc.nycu.edu.tw\/?p=148"},"modified":"2025-07-01T01:36:55","modified_gmt":"2025-07-01T01:36:55","slug":"%e5%b0%88%e5%ae%b6%e7%b0%a1%e4%bb%8b%ef%bc%9a%e9%8d%be%e5%bf%97%e5%ae%8f","status":"publish","type":"post","link":"https:\/\/genoinfocore.crc.nycu.edu.tw\/?p=148","title":{"rendered":"\u5c08\u5bb6\u7c21\u4ecb\uff1a\u937e\u5fd7\u5b8f"},"content":{"rendered":"\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/genoinfocore.crc.nycu.edu.tw\/?p=86\">\u9ede\u6211\u9810\u7d04<\/a><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u937e\u5fd7\u5b8f \u535a\u58eb\u5177\u5099\u751f\u547d\u79d1\u5b78\u80cc\u666f\u8207\u5206\u5b50\u751f\u7269\u5be6\u9a57\u5ba4\u8a13\u7df4\uff0c\u5c08\u9577\u65bc\u7d50\u5408\u81e8\u5e8a\u554f\u984c\u8207\u57fa\u790e\u7814\u7a76\u79d1\u5b78\u7814\u7a76\u7684\u8f49\u8b6f\u91ab\u5b78\u7814\u7a76\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7814\u7a76\u9818\u57df\uff1a<\/strong><br>\u81e8\u5e8a\u982d\u9838\u764c\u764c\u75c7\u8f49\u79fb\u5206\u5b50\u751f\u7269\u7814\u7a76<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u5b78\u6b77\uff1a<\/strong><br>\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78\u4e2d\u7814\u9662\u570b\u969b\u7814\u7a76\u751f\u5206\u5b50\u91ab\u5b78\u535a\u58eb\u5b78\u4f4d\u5b78\u7a0b\u535a\u58eb<br>\u570b\u7acb\u967d\u660e\u5927\u5b78\u751f\u5316\u66a8\u5206\u5b50\u751f\u7269\u7814\u7a76\u6240\u78a9\u58eb<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7d93\u6b77\uff1a<\/strong><br>\u570b\u7acb\u967d\u660e\u5927\u5b78\u81e8\u5e8a\u91ab\u5b78\u7814\u7a76\u6240\u535a\u58eb\u5f8c<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u5c08\u9577\uff1a<\/strong><br>\u5206\u5b50\u751f\u7269\u6280\u8853\u8207\u816b\u7624\u5c0f\u9f20\u6a21\u578b\uff08PDX, Immune cell profiling\uff09<br>\u8f49\u9304\u9ad4\u5b9a\u5e8f\u6578\u64da\u5206\u6790\uff08Single cell RNAseq\uff09<br>\u7a7a\u9593\u8f49\u9304\u9ad4RNA\u5206\u6790\uff0810x VISIUM\uff09<br>\u9ad8\u901a\u91cf\u87a2\u5149\u81e8\u5e8a\u6aa2\u9ad4\u8868\u73fe\u5206\u6790\uff08Vectra Polariss\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7814\u7a76\u6210\u679c\uff1a<\/strong><br>1. Chih-Hung Chung, Chun-Yu Lin, Chih-Yu Chen, Chun-Wei Hsueh, Pen-Yuan Chu, Shyh-Kuan Tai and Muh-Hwa Yang Ferroptosis signature shapes the immune profiles to enhance the response to immune checkpoint inhibitors in head and neck cancer Advanced Science (2023) doi:10.1002\/advs.202204514<br>2. Da-Liang Ou, Chia-Wei Chen, Chia-Lang Hs, Chih-Hung Chung, Zi-Rui Feng, Bin-Shyun Lee, Ann-Lii Cheng, Muh-Hwa Yang,Chiun Hsu Regorafenib enhances antitumor immunity via inhibition of p38 kinase\/Creb1\/Klf4 axis in tumor-associated macrophages J Immunother Cancer (2021) DOI: 10.1136\/jitc-2020-001657<br>3. Lin SC, Chung CH, Chung CH, Kuo MH, Hsieh CH, Chiu YF, Shieh YS, Chou YT, Wu CW OCT4B mediates hypoxia-induced cancer dissemination. Oncogene. (2019) doi: 10.1038\/s41388-018-0487-6Y-T Chou, C-H Hsieh, S-H<br>4. Lin SC, Chou YT, Jiang SS, Chang JL, Chung CH, Kao YR, Chang IS, Wu CW (2016) Epigenetic Switch between SOX2 and SOX9 Regulates Cancer Cell Plasticity. Cancer Res. (1 Dec 2016) doi: 10.1158\/0008-5472<br>5. Chiou, C-F Hsu, Y-R Kao, C-C Lee, C-H Chung, Y-H Wang, H-S Hsu, S-T Pang, Y-S Shieh and C-W Wu. (2012) CITED2 functions as a molecular switch of cytokine-induced proliferation and quiescence. Cell Death &amp; Differentiation , (2012) | doi:10.1038\/cdd.2012.91<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u937e\u5fd7\u5b8f \u535a\u58eb\u5177\u5099\u751f\u547d\u79d1\u5b78\u80cc\u666f\u8207\u5206\u5b50\u751f\u7269\u5be6\u9a57\u5ba4\u8a13\u7df4\uff0c\u5c08\u9577\u65bc\u7d50\u5408\u81e8\u5e8a\u554f\u984c\u8207\u57fa\u790e\u7814\u7a76\u79d1\u5b78\u7814\u7a76\u7684\u8f49\u8b6f\u91ab\u5b78\u7814\u7a76\u3002 \u7814\u7a76\u9818 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":478,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-148","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-consultation"],"blocksy_meta":[],"jetpack_featured_media_url":"https:\/\/genoinfocore.crc.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/11.png","_links":{"self":[{"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/148","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=148"}],"version-history":[{"count":3,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/148\/revisions"}],"predecessor-version":[{"id":491,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/148\/revisions\/491"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/media\/478"}],"wp:attachment":[{"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=148"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=148"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=148"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}