{"id":142,"date":"2025-06-24T06:39:35","date_gmt":"2025-06-24T06:39:35","guid":{"rendered":"https:\/\/genoinfocore.crc.nycu.edu.tw\/?p=142"},"modified":"2025-07-01T01:37:15","modified_gmt":"2025-07-01T01:37:15","slug":"%e5%b0%88%e5%ae%b6%e7%b0%a1%e4%bb%8b%ef%bc%9a%e5%bc%b5%e8%80%80%e6%96%87","status":"publish","type":"post","link":"https:\/\/genoinfocore.crc.nycu.edu.tw\/?p=142","title":{"rendered":"\u5c08\u5bb6\u7c21\u4ecb\uff1a\u5f35\u8000\u6587"},"content":{"rendered":"\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/genoinfocore.crc.nycu.edu.tw\/?p=84\">\u9ede\u6211\u9810\u7d04<\/a><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u5f35\u8000\u6587 \u52a9\u7406\u7814\u7a76\u54e1 \u535a\u58eb\u5177\u5099\u91ab\u5b78\u6aa2\u9a57\u76f8\u95dc\u80cc\u666f\u8207\u570b\u5916\u5be6\u9a57\u5ba4\u8a13\u7df4\uff0c\u5c08\u7cbe\u65bc\u5c0f\u9f20\u764c\u75c7\u6a21\u5f0f\u8207\u51b7\u87a2\u5149\u5f71\u50cf\u7cfb\u7d71\u5206\u6790\u5efa\u7acb\uff0c\u517c\u5177\u8c50\u5bcc\u514d\u75ab\u7d30\u80de\u5206\u6790\u8207\u76f8\u95dc\u6297\u9ad4\u85e5\u7269\u6cbb\u7642\u7d93\u9a57\uff0c\u53ef\u63d0\u4f9b\u81e8\u5e8a\u524d\u5be6\u9a57\u8a2d\u8a08\u8207\u5f71\u50cf\u5206\u6790\u8aee\u8a62\u8207\u5efa\u8b70\uff0c\u6b61\u8fce\u9810\u7d04\u8a0e\u8ad6\u8207\u6d3d\u8ac7\u5408\u4f5c\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7814\u7a76\u9818\u57df\uff1a<\/strong><br>\u5c0f\u9f20\u764c\u6a21\u5f0f\u7cfb\u7d71\u5efa\u7acb\u8207\u5f71\u50cf\u5206\u6790\u3001\u816b\u7624\u6cbb\u7642\u514d\u75ab\u5206\u6790\u3001\u5c0f\u5206\u5b50\u8207\u86cb\u767d\u85e5\u7269\u958b\u767c\u7642\u6548\u8a55\u4f30\u3001\u6297\u51dd\u8840\u8207\u767c\u708e\u85e5\u7269\u958b\u767c<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u5b78\u6b77\uff1a<\/strong><br>\u9577\u5e9a\u5927\u5b78\u751f\u7269\u91ab\u5b78\u7814\u7a76\u6240\u535a\u58eb<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7d93\u6b77\uff1a<\/strong><br>\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78\u52a9\u7406\u7814\u7a76\u54e1<br>\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \u81e8\u5e8a\u91ab\u5b78\u7814\u7a76\u6240\u535a\u58eb\u5f8c<br>\u65e5\u672c\u6771\u5317\u5927\u5b78 \u91ab\u5b78\u90e8 \u5148\u9032\u6cbb\u7642\u8207\u8f49\u8b6f\u7814\u7a76\u4e2d\u5fc3\u7814\u7a76\u54e1<br>\u65e5\u672c\u6771\u5317\u5927\u5b78 \u91ab\u5b78\u90e8 \u6297\u9ad4\u5275\u85e5\u5206\u91ce\u7522\u5b98\u5b78\u7814\u7a76\u54e1<br>\u9577\u5e9a\u5927\u5b78\u751f\u7269\u91ab\u5b78\u7814\u7a76\u6240\u535a\u58eb\u5f8c<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u5c08\u9577\uff1a<\/strong><br>\u5c0f\u9f20\u6d3b\u9ad4\u5f71\u50cf\u5206\u6790\u8207\u764c\u75c7\u6a21\u5f0f\u5efa\u7acb\uff08IVIS, animal model\uff09<br>\u816b\u7624\u514d\u75ab\u6cbb\u7642\u8207\u7d30\u80de\u5206\u6790\uff08Immunotherapy &amp; Immune cell analysis\uff09<br>\u6297\u51dd\u8840\uff0f\u767c\u708e\u85e5\u7269\u958b\u767c\uff08\u7642\u6548\u8a55\u4f30\u8207\u81e8\u5e8a\u524d\u52d5\u7269\u6e2c\u8a66\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u8b49\u7167\uff1a<\/strong><br>\u8f3b\u5c04\u64cd\u4f5c\u5b89\u5168\u8b49\u66f8<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7814\u7a76\u6210\u679c\uff1a<\/strong><br>1. Chang YW, Hsiao HW, Chen JP, Tzeng SF, Tsai CH, Wu CY, Hsieh HH, Carmona. SJ, Andreatta M, Conza GD, Su MT, Koni PA, Ho PC, Chen HK, Yang MH. A CSF-1R-blocking antibody\/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells. (2023) Cell Reports Medicine<br>2. Chung CH, Lin CY, Chen CY, Hsueh CW, Chang YW, Wang CC, Chu PY, Tai SK, Yang MH. Ferroptosis Signature Shapes the Immune Profiles to Enhance the Response to Immune Checkpoint Inhibitors in Head and Neck Cancer. (2023) Advanced Science)<br>3. Chen YH, Hsu JY, Chu CT, Chang YW, Fan JR, Yang MH, Chen HC. Loss of cell-cell adhesion triggers cell migration through Rac1-dependent ROS generation. (2022) Life Sci Alliance.<br>4. Tseng CP, Huang YL, Chang YW, Liao HR, Chen YL, Hsieh PW. Polysaccharide-containing fraction from Artemisia argyi inhibits tumor cell-induced platelet aggregation by blocking interaction of podoplanin with C-type lectin-like receptor 2. (2020) J Food Drug Anal.<br>5. Chang YW, Kaneko MK, Yamada S, Kato Y. Epitope Mapping of Monoclonal Antibody PMab-52 Against Cat Podoplanin. (2018) Monoclon Antib Immunodiagn Immunother.<br>6. Sun DS, Chang YW, Kau JH, Huang HH, Ho PH, Tzeng YJ, Chang HH. Soluble P-selectin rescues mice from anthrax lethal toxin-induced mortality through PSGL-1 pathway-mediated correction of hemostasis. (2017) Virulence.<br>7. Chang YW, Tseng CP, Lee CH, Hwang TL, Chen YL, Su MT, Chong KY, Lan YW, Wu CC, Chen KJ, Lu FH, Liao HR, Hsueh C, Hsieh PW. \u03b2-Nitrostyrene derivatives attenuate LPS-mediated acute lung injury via the inhibition of neutrophil-platelet interactions and NET release.(2018) Am J Physiol Lung Cell Mol Physiol.<br>8. Chang YW, Hsieh PW, Chang YT, Lu MH, Huang TF, Chong KY, Liao HR, Cheng JC ,Tseng CP. Identification of a novel platelet antagonist that binds to CLEC-2 and suppresses podoplanin-induced platelet aggregation and cancer metastasis. (2015) Oncotarget.<br>9. Tsai HJ, Huang CL, Chang YW, Huang DY, Lin CC, Cooper JA, Cheng JC, Tseng CP. Disabled-2 is required for efficient hemostasis and platelet activation by thrombin in mice. (2014) Arterioscler Thromb Vasc Biol.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5f35\u8000\u6587 \u52a9\u7406\u7814\u7a76\u54e1 \u535a\u58eb\u5177\u5099\u91ab\u5b78\u6aa2\u9a57\u76f8\u95dc\u80cc\u666f\u8207\u570b\u5916\u5be6\u9a57\u5ba4\u8a13\u7df4\uff0c\u5c08\u7cbe\u65bc\u5c0f\u9f20\u764c\u75c7\u6a21\u5f0f\u8207\u51b7\u87a2\u5149\u5f71\u50cf\u7cfb\u7d71\u5206\u6790\u5efa\u7acb\uff0c\u517c\u5177 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":477,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-142","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-consultation"],"blocksy_meta":[],"jetpack_featured_media_url":"https:\/\/genoinfocore.crc.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/9.png","_links":{"self":[{"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/142","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=142"}],"version-history":[{"count":2,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/142\/revisions"}],"predecessor-version":[{"id":217,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/142\/revisions\/217"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/media\/477"}],"wp:attachment":[{"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=142"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=142"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/genoinfocore.crc.nycu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=142"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}