{"id":130,"date":"2025-06-24T03:25:34","date_gmt":"2025-06-24T03:25:34","guid":{"rendered":"https:\/\/genoinfocore.crc.nycu.edu.tw\/?p=130"},"modified":"2025-07-01T01:38:38","modified_gmt":"2025-07-01T01:38:38","slug":"%e5%b0%88%e5%ae%b6%e7%b0%a1%e4%bb%8b%ef%bc%9a%e9%99%b3%e5%bb%ba%e9%8b%92","status":"publish","type":"post","link":"https:\/\/genoinfocore.crc.nycu.edu.tw\/?p=130","title":{"rendered":"\u5c08\u5bb6\u7c21\u4ecb\uff1a\u9673\u5efa\u92d2"},"content":{"rendered":"\n
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\u9ede\u6211\u9810\u7d04<\/a><\/div>\n<\/div>\n\n\n\n

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\u7814\u7a76\u9818\u57df\uff1a<\/strong>
Genomics, Oncology<\/p>\n\n\n\n

\u5b78\u6b77\uff1a<\/strong>
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\u5927\u540c\u5de5\u5b78\u9662\u751f\u7269\u5de5\u7a0b\u7cfb\u5b78\u58eb <\/p>\n\n\n\n

\u7d93\u6b77\uff1a<\/strong>
\u570b\u7acb\u967d\u660e\u5927\u5b78\u69ae\u967d\u57fa\u56e0\u9ad4\u7814\u7a76\u4e2d\u5fc3\u52a9\u7406\u7814\u7a76\u54e1
\u4e2d\u592e\u7814\u7a76\u9662\u751f\u7269\u91ab\u5b78\u7814\u7a76\u6240\u535a\u58eb\u5f8c\u7814\u7a76\u54e1<\/p>\n\n\n\n

\u5c08\u9577\uff1a<\/strong>
Chromosome aberration analysis
Gene expression analysis
Genotyping analysis, Public domai<\/p>\n\n\n\n

\u7814\u7a76\u6210\u679c\uff1a<\/strong>
1. Yang, C.Y., Tseng, J.Y., Chen, C.F. , Chou, T.Y., Gao, H.W., Hua, C.L., Lin, C.H., Lin, J.K., and Jiang, J.K., Genome-wide copy number changes and CD133 expression characterized distinct subset of colon polyps: differentiation between incidental polyps and cancer-associated polyps. Int J Colorectal Dis, 2015. ( Equal first author)
2. Sudhir, P.R., Lin, S.T., Chia-Wen, C., Yang, S.H., Li, A.F., Lai, R.H., Wang, M.J., Chen, Y.T., Chen, C.F., Jou, Y.S., and Chen, J.Y., Loss of PTPRM associates with the pathogenic development of colorectal adenoma-carcinoma sequence. Sci Rep, 2015. 5: p. 9633.
3. Chou, C.P., Huang, N.C., Jhuang, S.J., Pan, H.B., Peng, N.J., Cheng, J.T., Chen, C.F., Chen, J.J., and Chang, T.H., Ubiquitin-Conjugating Enzyme UBE2C Is Highly Expressed in Breast Microcalcification Lesions. Plos One 2014. 9(4): p. e93934.
4. Wang, Y.W., Lin, K.T., Chen, S.C., Gu, D.L., Chen, C.F., Tu, P.H., and Jou, Y.S., Overexpressed-eIF3I interacted and activated oncogenic Akt1 is a theranostic target in human hepatocellular carcinoma. Hepatology, 2013. 58(1): p. 239-50.
5. Gu, D.L., Chen, Y.H., Shih, J.H., Lin, C.H., Jou, Y.S., and Chen, C.F., Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma. World J Gastroenterol, 2013. 19(47): p. 8873-8879.
6. Kao, S., Shiau, C.K., Gu, D.L., Ho, C.M., Su, W.H., Chen, C.F., Lin, C.H., and Jou, Y.S., IGDB.NSCLC: integrated genomic database of non-small cell lung cancer. Nucleic Acids Res, 2012. 40(Database issue): p. D972-7.
7. Shiau, C.K., Gu, D.L., Chen, C.F., Lin, C.H., and Jou, Y.S., IGRhCellID: integrated genomic resources of human cell lines for identification. Nucleic Acids Res, 2011. 39(Database issue): p. D520-4.
8. Chen, C.F., Hsu, E.C., Lin, K.T., Tu, P.H., Chang, H.W., Lin, C.H., Chen, Y.J., Gu, D.L., Wu, J.Y., Chen, Y.T., Hsu, M.T., and Jou, Y.S., Overlapping high-resolution copy number alterations in cancer genomes identified putative cancer genes in hepatocellular carcinoma. Hepatology, 2010. 52(5): p. 1690-701.
9. Chen, C.F., Yeh, S.H., Chen, D.S., Chen, P.J., and Jou, Y.S., Molecular genetic evidence supporting a novel human hepatocellular carcinoma tumor suppressor locus at 13q12.11. Genes Chromosomes Cancer, 2005. 44(3): p. 320-8.
10. Lee, J.M., Chung, C.Y., Chiang, W.W., Liou, Y.H., Chen, C.F., and Liao, N.S., IL-15Ralpha is a negative regulator of TCR-activated proliferation in CD4+ T cells. J Immunol, 2004. 173(5): p. 3155-64.
11. Jou, Y.S., Lee, C.S., Chang, Y.H., Hsiao, C.F., Chen, C.F., Chao, C.C., Wu, L.S., Yeh, S.H., Chen, D.S., and Chen, P.J., Clustering of minimal deleted regions reveals distinct genetic pathways of human hepatocellular carcinoma. Cancer Res, 2004. 64(9): p. 3030-6.<\/p>\n","protected":false},"excerpt":{"rendered":"

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