Expert Profile: Chen, Chian-Feng

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Hi….我是陽明大學榮陽基因體研究中心的助理研究員 陳建鋒，參事基因體研究多年，特別是在 GWAS 及Cancer Genomic 的方面有很多經驗，歡迎您來跟我討論。

Field:

Genomics, Oncology

Education/Experience:

Education：

Ph.D.      Life Science           National Defense Medical Center, Taipei,                                                                     Taiwan

M.S.        Radiobiology        National Tsing Hua University, Hsinchu,                                                                     Taiwan

B.S.         Bioengineering    Tatung Institute of Technology, Taipei,                                                                                 Taiwan

Experiences：

Assistant Research Fellow   VYM Genome Research Center, National Yang Ming University, Taipei, Taiwan

Postdoctoral Fellow             Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan

Specialties:

Chromosome aberration analysis, Gene expression analysis, Genotyping analysis, Public domain data mining

Publications:

  1. Yang, C.Y., Tseng, J.Y., Chen, C.F. *, Chou, T.Y., Gao, H.W., Hua, C.L., Lin, C.H., Lin, J.K., and Jiang, J.K., Genome-wide copy number changes and CD133 expression characterized distinct subset of colon polyps: differentiation between incidental polyps and cancer-associated polyps. Int J Colorectal Dis, 2015. (* Equal first author)
  2. Sudhir, P.R., Lin, S.T., Chia-Wen, C., Yang, S.H., Li, A.F., Lai, R.H., Wang, M.J., Chen, Y.T., Chen, C.F., Jou, Y.S., and Chen, J.Y., Loss of PTPRM associates with the pathogenic development of colorectal adenoma-carcinoma sequence. Sci Rep, 2015. 5: p. 9633.
  3. Chou, C.P., Huang, N.C., Jhuang, S.J., Pan, H.B., Peng, N.J., Cheng, J.T., Chen, C.F., Chen, J.J., and Chang, T.H., Ubiquitin-Conjugating Enzyme UBE2C Is Highly Expressed in Breast Microcalcification Lesions. Plos One 2014. 9(4): p. e93934.
  4. Wang, Y.W., Lin, K.T., Chen, S.C., Gu, D.L., Chen, C.F., Tu, P.H., and Jou, Y.S., Overexpressed-eIF3I interacted and activated oncogenic Akt1 is a theranostic target in human hepatocellular carcinoma. Hepatology, 2013. 58(1): p. 239-50.
  5. Gu, D.L., Chen, Y.H., Shih, J.H., Lin, C.H., Jou, Y.S., and Chen, C.F., Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma. World J Gastroenterol, 2013. 19(47): p. 8873-8879.
  6. Kao, S., Shiau, C.K., Gu, D.L., Ho, C.M., Su, W.H., Chen, C.F., Lin, C.H., and Jou, Y.S., IGDB.NSCLC: integrated genomic database of non-small cell lung cancer. Nucleic Acids Res, 2012. 40(Database issue): p. D972-7.
  7. Shiau, C.K., Gu, D.L., Chen, C.F., Lin, C.H., and Jou, Y.S., IGRhCellID: integrated genomic resources of human cell lines for identification. Nucleic Acids Res, 2011. 39(Database issue): p. D520-4.
  8. Chen, C.F., Hsu, E.C., Lin, K.T., Tu, P.H., Chang, H.W., Lin, C.H., Chen, Y.J., Gu, D.L., Wu, J.Y., Chen, Y.T., Hsu, M.T., and Jou, Y.S., Overlapping high-resolution copy number alterations in cancer genomes identified putative cancer genes in hepatocellular carcinoma. Hepatology, 2010. 52(5): p. 1690-701.
  9. Chen, C.F., Yeh, S.H., Chen, D.S., Chen, P.J., and Jou, Y.S., Molecular genetic evidence supporting a novel human hepatocellular carcinoma tumor suppressor locus at 13q12.11. Genes Chromosomes Cancer, 2005. 44(3): p. 320-8.
  10. Lee, J.M., Chung, C.Y., Chiang, W.W., Liou, Y.H., Chen, C.F., and Liao, N.S., IL-15Ralpha is a negative regulator of TCR-activated proliferation in CD4+ T cells. J Immunol, 2004. 173(5): p. 3155-64.
  11. Jou, Y.S., Lee, C.S., Chang, Y.H., Hsiao, C.F., Chen, C.F., Chao, C.C., Wu, L.S., Yeh, S.H., Chen, D.S., and Chen, P.J., Clustering of minimal deleted regions reveals distinct genetic pathways of human hepatocellular carcinoma. Cancer Res, 2004. 64(9): p. 3030-6.

Hi….我是陽明大學榮陽基因體研究中心的助理研究員 陳建鋒，參事基因體研究多年，特別是在 GWAS 及Cancer Genomic 的方面有很多經驗，歡迎您來跟我討論。

Field:

Genomics, Oncology

Education/Experience:

Education：

Ph.D.      Life Science           National Defense Medical Center, Taipei,                                                                     Taiwan

M.S.        Radiobiology        National Tsing Hua University, Hsinchu,                                                                     Taiwan

B.S.         Bioengineering    Tatung Institute of Technology, Taipei,                                                                                 Taiwan

Experiences：

Assistant Research Fellow   VYM Genome Research Center, National Yang Ming University, Taipei, Taiwan

Postdoctoral Fellow             Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan

Specialties:

Chromosome aberration analysis, Gene expression analysis, Genotyping analysis, Public domain data mining

Publications:

  1. Yang, C.Y., Tseng, J.Y., Chen, C.F. *, Chou, T.Y., Gao, H.W., Hua, C.L., Lin, C.H., Lin, J.K., and Jiang, J.K., Genome-wide copy number changes and CD133 expression characterized distinct subset of colon polyps: differentiation between incidental polyps and cancer-associated polyps. Int J Colorectal Dis, 2015. (* Equal first author)
  2. Sudhir, P.R., Lin, S.T., Chia-Wen, C., Yang, S.H., Li, A.F., Lai, R.H., Wang, M.J., Chen, Y.T., Chen, C.F., Jou, Y.S., and Chen, J.Y., Loss of PTPRM associates with the pathogenic development of colorectal adenoma-carcinoma sequence. Sci Rep, 2015. 5: p. 9633.
  3. Chou, C.P., Huang, N.C., Jhuang, S.J., Pan, H.B., Peng, N.J., Cheng, J.T., Chen, C.F., Chen, J.J., and Chang, T.H., Ubiquitin-Conjugating Enzyme UBE2C Is Highly Expressed in Breast Microcalcification Lesions. Plos One 2014. 9(4): p. e93934.
  4. Wang, Y.W., Lin, K.T., Chen, S.C., Gu, D.L., Chen, C.F., Tu, P.H., and Jou, Y.S., Overexpressed-eIF3I interacted and activated oncogenic Akt1 is a theranostic target in human hepatocellular carcinoma. Hepatology, 2013. 58(1): p. 239-50.
  5. Gu, D.L., Chen, Y.H., Shih, J.H., Lin, C.H., Jou, Y.S., and Chen, C.F., Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma. World J Gastroenterol, 2013. 19(47): p. 8873-8879.
  6. Kao, S., Shiau, C.K., Gu, D.L., Ho, C.M., Su, W.H., Chen, C.F., Lin, C.H., and Jou, Y.S., IGDB.NSCLC: integrated genomic database of non-small cell lung cancer. Nucleic Acids Res, 2012. 40(Database issue): p. D972-7.
  7. Shiau, C.K., Gu, D.L., Chen, C.F., Lin, C.H., and Jou, Y.S., IGRhCellID: integrated genomic resources of human cell lines for identification. Nucleic Acids Res, 2011. 39(Database issue): p. D520-4.
  8. Chen, C.F., Hsu, E.C., Lin, K.T., Tu, P.H., Chang, H.W., Lin, C.H., Chen, Y.J., Gu, D.L., Wu, J.Y., Chen, Y.T., Hsu, M.T., and Jou, Y.S., Overlapping high-resolution copy number alterations in cancer genomes identified putative cancer genes in hepatocellular carcinoma. Hepatology, 2010. 52(5): p. 1690-701.
  9. Chen, C.F., Yeh, S.H., Chen, D.S., Chen, P.J., and Jou, Y.S., Molecular genetic evidence supporting a novel human hepatocellular carcinoma tumor suppressor locus at 13q12.11. Genes Chromosomes Cancer, 2005. 44(3): p. 320-8.
  10. Lee, J.M., Chung, C.Y., Chiang, W.W., Liou, Y.H., Chen, C.F., and Liao, N.S., IL-15Ralpha is a negative regulator of TCR-activated proliferation in CD4+ T cells. J Immunol, 2004. 173(5): p. 3155-64.
  11. Jou, Y.S., Lee, C.S., Chang, Y.H., Hsiao, C.F., Chen, C.F., Chao, C.C., Wu, L.S., Yeh, S.H., Chen, D.S., and Chen, P.J., Clustering of minimal deleted regions reveals distinct genetic pathways of human hepatocellular carcinoma. Cancer Res, 2004. 64(9): p. 3030-6.

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